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当前位置: 首页 > 产品中心 > peptide > Dojindo/DTPA酸酐/5/D033
商品详细Dojindo/DTPA酸酐/5/D033
Dojindo/DTPA酸酐/5/D033
Dojindo/DTPA酸酐/5/D033
商品编号: D033
品牌: 同仁
市场价: ¥7200.00
美元价: 4320.00
产地: 美国(厂家直采)
公司:
产品分类: 多肽合成
公司分类: peptide
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍
DescriptionReferencesS.D.S
Product Description of Amine-Reactive BiotinsDTPA anhydride is utilized to add chelate functions to molecules or surfaces with amine groups. After adding chelate functions, metal ions such as radioisotopes can be introduced to the molecule. According to Dr. Hnatowich, IgG may be labeled with radioactive indium using DTPA-anhydride. DTPA is first linked to IgG through a covalent bond, then In(III) is tightly chelated to DTPA. Such radioactive antibodies are known to bind with antigen in vitro and in vivo.

Structural Formula:

1. W. C. Eckelman, S. M. Karesh and R. C. Reba, New Compounds: Fatty Acid and Long Chain Hydrocarbon Derivatives Containing a Strong Chelating Agent, J. Pharm. Sci., 1975, 64, 704.2. B. A. Khaw, J. T. Fallon, H. W. Strauss and E. Haber, Myocardial Infarct Imaging of Antibodies to Canine Cardiac Myosin with Indium-111-Diethylenetriamine pentaacetic acid, Science, 1980, 209, 295.3. D. J. Hnatowich, W. W. Layne and R. L. Childs, The Preparation and Labeling of DTPA-Coupled Albumin, J. Appl. Radiat. Isot., 1982, 33, 327.4. D. J. Hnatowich, W. W. Layne, R. L. Childs, D. Lanteigne, M. A. Davis, T. W. Griffin and P. W. Doherty, Radioactive Labeling of Antibody: A Simple and Efficient Method, Science, 1983, 220, 613.5. C. F. Meares and D. A. Goodwin, Linking Radiometals to Proteins with Bifunctional Chelating Agents, J. Protein Chem. , 1984, 3, 215.6. A. Canfi, M. P. Bailey and B. F. Rocks, Fluorescent Terbium Chelates Derived from Diethylenetriaminepentaacetic Acid and Heterocyclic Compounds, Analyst, 1989, 114, 1405.7. C. H. Paik, K. Yokoyama, J. C. Reynolds, S. M. Quadri, C. Y. Min, S. Y. Shin, P. J. Maloney, S. M. Larson and R. C. Reba, Reduction of Background Activities by Introduction of a Diester Linkage between Antibody and a Chelatein Radioimmunodetection of Tumor, J. Nuclear Medicine, 1989, 30, 1693.8. D. J. Hnatowich, Recent Developments in the Radiolabeling of Antibodies with iodine, Indium, and Technetium, Semi. Nucl. Medicine, 1990, 20, 80.

Related Categories

Labeling Chemistry
品牌介绍
Dojindo细胞分析细胞活力和细胞毒性测定用于药物筛选和化学物质的细胞毒性测试。Dojindo开发了高度水溶性的四唑盐,称为WST。WST-8是高度稳定的WST,用于Cell Counting Kit-8(CCK-8)。由于WST-8甲maz是水溶性的,因此不会形成晶体。因此,不需要诸如MTT测定的增溶过程。此外,CCK-8的检测灵敏度高于其他四唑盐,例如MTT,XTT,MTS或WST-1。WST检测机制 ß-半乳糖苷酶检测试剂细胞增殖/细胞毒性转染细胞染色细胞内荧光探针细菌染色微生物活力测定干细胞分化SPiDER-ßGal线粒体检测细胞代谢应用产品展示细胞生长检测,药物筛选,比色/荧光检测细胞计数试剂盒-8细胞计数试剂盒8 + 96孔有机硅定向剂细胞计数试剂盒-F细胞毒性LDH检测试剂盒-WST 96孔有机硅定向剂MTT了解检测机制的差异:点击这里细胞周期分析细胞周期测定溶液深红色细胞周期测定溶液蓝色